Do Sharks Get Cancer: The Science Behind the Myth

Lemon shark (Negaprion brevirostris) releasing air bubbles while swimming in the water

For decades, one of the most fascinating and persistent beliefs in marine biology has been the idea that sharks are immune to cancer. The phrase do sharks get cancer often sparks curiosity among scientists, divers, and the general public alike. This belief has contributed to a widespread myth, fueled by anecdotal claims and commercial interests promoting shark cartilage as a cancer treatment. But how much truth is there to this idea, and what does modern science say about sharks and cancer?

In this article, we will explore the facts behind the shark cancer myth, review the scientific evidence of shark tumor cases, and examine the unique features of the shark immune system and shark biology that contribute to their reputation for cancer resistance in animals.

So, Do Sharks Get Cancer?

Close-up of juvenile grey reef shark (Carcharhinus amblyrhynchos)
Grey Reef Shark | Photo by Christel Sagniez via Pixabay

Despite popular belief, sharks can get cancer. The myth that sharks are immune to cancer has been disproven by scientific studies and documented medical cases. Researchers have observed tumors in several shark species, including those affecting the liver, skin, and gastrointestinal tract. The first known tumor in a wild shark was recorded in 1908, and dozens of similar cases have been identified since then.

However, what makes sharks interesting to researchers is not their total immunity, but the possibility that they are less prone to cancer than many other animals. This has sparked curiosity about whether certain traits in shark biology contribute to a form of resistance, leading to ongoing studies in comparative oncology.

The Origins of the Shark Cancer Myth

Collection of different body parts of sharks, including fins and tongues
Shark Body Parts Stored in Containers in Chinese Medicine | Photo by Chris 73, CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

The shark cancer myth began gaining traction in the 1990s, largely due to the popularity of books and health products that claimed shark cartilage could cure or prevent cancer. These claims were based on preliminary studies suggesting that compounds in shark cartilage might inhibit the growth of blood vessels in tumors. This concept, known as anti-angiogenesis, has become the foundation of a billion-dollar supplement industry.

Unfortunately, the early hype outpaced the science. Later studies revealed that most of the original research had limitations, and clinical trials involving shark cartilage cancer supplements failed to show consistent or significant benefits. Yet the myth persisted, in part because sharks seem so ancient, mysterious, and robust in their environments.

What the Science Really Says About Sharks and Cancer

Two scientists working in a laboratory
Scientist Working in a Lab | Photo by Edward Jenner via Pexels

Scientists have confirmed that sharks are not immune to cancer, but they remain compelling models for understanding cancer resistance in animals. The rate of tumors in sharks appears to be relatively low compared to many other species, particularly mammals. This raises important questions about what biological factors may be offering some level of protection.

Some researchers believe the shark’s immune system plays a central role. Sharks possess a highly evolved immune system, featuring robust antimicrobial defenses and unique antibodies known as IgNARs. These adaptations help sharks fight off infections and possibly suppress tumor development at early stages.

Unique Features of Shark Biology

Tiger shark (Galeocerdo cuvier) swimming near sandy seabed in clear blue water on a sunny day
Tiger Shark | Photo by Gerald Schömbs via Unsplash

One factor that may contribute to why sharks don’t get sick as often as other marine animals is their simple yet efficient physiology. Sharks possess a cartilaginous skeleton, which is less vascularized than bone. This could limit the formation of certain types of tumors, especially those that rely on dense blood vessel networks.

Another area of interest is the chemical composition of shark tissues. Certain shark species produce compounds like squalamine, a molecule with demonstrated antiviral and anti-cancer properties in laboratory settings. While promising, more research is needed to determine how these compounds function within the shark’s body and whether they could be used in human medicine.

Documented Shark Tumor Cases

Scuba diver photographing a hammerhead shark in clear water
Scuba Diver and a Hammerhead Shark | Photo by Walter Torres via Pexels

Although they are rare, well-documented cases of shark tumors exist in both wild and captive populations. Scientists have observed cancers in various species, including the dusky shark, sand tiger shark, and bull shark. These tumors have affected organs such as the liver, intestines, and reproductive systems.

In some cases, external tumors have been visible on the skin or fins. These findings are significant because they provide direct evidence against the belief that sharks are completely cancer-free. The presence of cancer in sharks does not diminish their value to science, but it corrects a long-standing misunderstanding.

Shark Cartilage and the Misuse of Science

Blue shark (Prionace glauca) swimming in clear blue water during daytime
Blue Shark | Photo by Diego Delso, CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

The widespread marketing of shark cartilage cancer supplements has raised ethical and environmental concerns. Aside from the lack of solid evidence supporting their effectiveness, the harvesting of sharks for cartilage has contributed to overfishing and the decline of many shark populations. This demand puts pressure on already vulnerable species, many of which are slow to reproduce and recover.

Conservationists and scientists alike argue that baseless health claims should not come at the expense of marine biodiversity. As we continue to search for cancer treatments, it is crucial to distinguish between myth and evidence and protect the species we study.

Cancer Resistance in Animals: How Do Sharks Compare?

Tiny naked mole rat eating a carrot in a cave
Naked Mole-Rat | Photo by John Trainor, CC BY 2.0 https://creativecommons.org/licenses/by/2.0, via Wikimedia Commons

Sharks are not the only animals being studied for their potential resistance to cancer. Other species, such as elephants and naked mole-rats, have also demonstrated unique mechanisms for suppressing tumors. By comparing cancer resistance in animals, scientists aim to identify shared traits that may lead to new cancer prevention strategies in humans.

In this context, sharks offer a valuable perspective, particularly due to their long lifespans, ancient evolutionary lineage, and unique immune systems. The ongoing study of shark biology offers hope for medical breakthroughs while also deepening our understanding of life beneath the waves.

Why Sharks Don’t Get Sick as Often

Blacktip reef shark (Carcharhinus limbatus) swimming in majestic blue water
Blacktip Reef Shark | Photo by Charles J. Sharp, CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons

The question of why sharks don’t get sick as frequently as other marine creatures is still under investigation. Their powerful immune defenses, antimicrobial peptides, and unique white blood cells all contribute to their ability to fend off disease. These systems not only keep sharks healthy but may also help prevent abnormal cell growth, such as cancer.

In addition, sharks inhabit a wide range of environments, from shallow reefs to deep-sea trenches, and have adapted to various ecological conditions. This adaptability may have enabled them to evolve robust biological defenses that continue to fascinate modern scientists.

Can Sharks Get Cancer? Yes, But They’re Still Special

Silky shark (Carcharhinus falciformis) swimming in clear blue water during daytime
Silky Shark | Photo by Marc Taquet, CC BY 4.0 https://creativecommons.org/licenses/by/4.0, via Wikimedia Commons

The simple answer to the question of whether sharks get cancer is yes. But what sets them apart is how rarely they seem to develop tumors compared to many other animals. This rarity has made them an important focus for researchers studying cancer biology and potential treatment pathways.

While we must move beyond the myth of total immunity, studying sharks still holds promise for uncovering useful insights. These discoveries may eventually contribute to advancements in medicine while also reminding us of the value of conserving such extraordinary creatures.

Final Thoughts

Close-up image of a great hammerhead shark (Sphyrna mokarran) with an open mouth near sandy seabed
Great Hammerhead Shark | Photo by Gerald Schömbs via Unsplash

So, do sharks get cancer? The answer is yes, though it happens less frequently than in many other species. The belief that sharks are immune to cancer is a myth, but it is one rooted in fascinating truths about their biology. Their strong immune systems, unique cartilage structures, and resilience in harsh environments make sharks valuable subjects for scientific research.

As we continue exploring what makes sharks such remarkable survivors, separating fact from fiction helps guide both medical innovation and conservation efforts. Understanding the science behind the myth deepens our appreciation for these ancient predators and underscores the importance of protecting them. If you’re curious about more shark-related science, there’s an entire ocean of knowledge waiting to be explored.